Spring
Understanding Cardiac Calcium Signaling from Molecules to Systems
Abstract.
Hecht Lecture: Redesign of Vancomycin for Resistant Bacteria
ABSTRACT
A summary of studies on the total synthesis and evaluation of the vancomycin family of glycopeptide antibiotics, their ligand binding pocket redesign to address the underlying molecular basis of resistance, and their subsequent peripheral tailoring to address the emerging public health problem of vancomycin resistance will be presented.
Quantifying Oxygen’s Role in Promoting Aggressive Cancer Phenotypes With a Paper-Based 3D Culture Platform
Abstract:
Electrochemical Conversion of CO2 and CO to C2+ Chemicals
ABSTRACT
Electrocatalysis for Chemical Synthesis and Energy Conversion
Abstract:
Micellar Electrokinetic Focusing Driven by Ion Concentration Polarization
Abstract
Photoredox and Electrochemical Methods for C-N Bond Forming Reactions
Photoredox and Electrochemical Methods for C-N Bond Forming Reactions
Supramolecular Approaches to Advanced Functional Materials
ABSTRACT
In the "bottom-up" approach, materials and devices are constructed from molecules capable of assembling themselves by principles/methods of molecular recognition. Although well-defined assemblies can be engineered by exploiting various noncovalent interactions, there are limited methods in the literature regarding the design and analysis of self-guiding molecules for materials application in which there is a strategic integration of the self-assembling motif. The principal research conducted in the Watkins Group encompasses fundamental studies towards understanding the molecular assembly of complex systems as it relates to overall performance. Reported are design guidelines towards novel building blocks for functional materials—specifically those for applications in optoelectronic devices and biomaterials. The multi-step synthesis of these building blocks is discussed. Spectroscopic analysis, as well as characterization via transmission electron microscopy (TEM) and X-ray crystallography of the molecular components and their resulting supramolecular assemblies, reveal materials possessing properties that are comparable to—even surpass—those commonly reported in the literature. Results of this study will be employed towards further research in novel molecular components capable of yielding high performing materials.
Antibody affinity reagents and reproducibility:
Learning Objectives