Featured News

Chemistry Department receives full accreditation by ASBMB for our biochemistry undergraduate degree.

Featured Faculty

Please join chair, Jill Venton in congratulating Rebecca Pompano on receiving an inaugural Research Excellence Award at the University of Virginia.

Seminars

Jefferson Lecture - Re-imagining the Periodic Table: Sustainable Catalysis for the 21st Century

Jefferson Lecture - Re-imagining the Periodic Table: Sustainable Catalysis for the 21st Century

Dr. Paul Chirik | Princeton University

Hosted by Graduate Student Council
Friday, January 24, 2020
Examining the Dynamics of Glucose Regulation

Examining the Dynamics of Glucose Regulation

Dr. Mike Roper | Florida State University

Hosted by Professor James Landers

ABSTRACT

Islets of Langerhans are the endocrine portion of the pancreas responsible for maintaining glucose homeostasis via the regulated secretion of numerous hormones, most notably insulin and glucagon. Defects in the secretion of these hormones are associated with a number of metabolic diseases, including diabetes and the metabolic syndrome. The ability to measure these glucose-regulating peptides with high time resolution and sensitivity is necessary to fully resolve the secretion dynamics of these factors and to understand how they change at various disease stages.

In this talk, a number of analytical strategies our group has developed which enable monitoring of secretion with high time resolution will be discussed. These assays include multi-color electrophoretic affinity assays, electrochromatographic separations for small molecule transmitters, and fluorescence anisotropy immunoassays. A number of these assays have been integrated into microfluidic systems to enable monitoring of secretions as a function of time. Select applications of these devices will also be discussed including how groups of islets can coordinate their secretion in vivo into pulses that are necessary for proper glucose utilization.

Friday, January 31, 2020
Specific Inhibition of Heparanase by Glycopolymers for Cancer and Diabetic Therapeutics

Specific Inhibition of Heparanase by Glycopolymers for Cancer and Diabetic Therapeutics

Dr. Hien Nguyen | Wayne State University

Hosted by Professor Clifford Stains
Friday, February 14, 2020

Alumni Corner

Join our online network groups, keep us updated, and support faculty research, scholarships and fellowships. Read More...