UVA Chemistry People Schreibers

Stuart L. Schreiber

Director of Chemical Biology at the Broad Institute of Harvard and MIT and a Howard Hughes Medical Institute Investigator

Director of Chemical Biology at and Founding Member of the Broad Institute of Harvard and MIT, where he is a Investigator. He is also the Morris Loeb Professor of Chemistry and Chemical Biology at Harvard University. He is a member of the National Academy of Sciences and the American Academy of Arts & Sciences (1995).

Dr. Schreiber was born February 6, 1956 and raised in Virginia. After receiving a B.A. degree (conducting research with Richard Sundberg) at the University of Virginia in June of 1977, he carried out graduate studies at Harvard University under the supervision of R. B. Woodward and Y. Kishi. Following completion of his doctoral studies, he joined the faculty at Yale University in May of 1981. He was promoted to Associate Professor with tenure in 1984 and to Full Professor in 1986. In 1988, he returned to Harvard.

Dr. Schreiber is known for having developed systematic ways to explore biology, especially disease biology, using small molecules and for his role in the development of the field of chemical biology. Currently, the Schreiber group research is focused on:

  • Development of next-generation synthetic chemistry affording a transformative small-molecule screening collection.
  • Investigating small molecules using human primary cells in an environment that mimics their in vivo niche.
  • Exploiting the remarkable ability of genetic approaches to illuminate the roles of genes in biology and disease
  • Attempting to discover small molecules that increase pancreatic beta cell numbers and function using organ cultures of human primary pancreatic islets