Quantifying biochemistry in living cells

Increasingly, fluorescent tools are providing insight into the “dark matter” of the cellular milieu: small molecules, secondary metabolites, metals, and ions.  One of the great promises of such tools is the ability to quantify cellular signals in precise locations with high temporal resolution.  Yet this is coupled with the challenge of how to ensure that our tools are not perturbing the underlying biology and the need to systematically measure hundreds of individual cells over time.

Surface Chemistry and Spectroscopy

Surface chemistry focuses on achieving a molecular-level understanding and control of surface chemical reactions that are oftentimes central to the modern technologies that produce chemicals & fuels, semiconductor devices, nanoscale particles & thin films, biomedical devices, immunological therapies, and so on.  Consequently, surface chemistry is a common thread of research interest for many UVa chemistry faculty. Spectroscopy enabling the characterization of molecular identity, concentration, and dynamics is another near-universal interest of our chemistry faculty.

Organic Chemistry and Synthesis

Organic compounds are central to biological processes and have many practical applications, including in the pharmaceutical, agriculture, materials, and energy industries. The study of Organic Chemistry can enable a greater understanding of the structure, properties, and function of carbon-containing compounds toward the goal of designing next-generation solutions to societal challenges and increasing our knowledge about the chemistry of life.

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