Featured News

The Pompano Lab's research was featured in C&E News' coverage of the national ACS Conference.

Featured Students

13 students from the class of 2017 receive certification from The American Society for Biochemistry and Molecular Biology. Five of these students achieved certification with distinction.  

Seminars

Antibody affinity reagents and reproducibility:

Antibody affinity reagents and reproducibility:

Professor Bhupal Ban | UVA - Antibody Engineering & Technology Core

Hosted by Professor Rebecca Pompano - *NOTE: (Dell 2 Room 100)

Learning Objectives

  •       Trends for isolation of monoclonal antibodies
  •       Current  antibody reproducibility problem in academic institute
  •       Antibody validation: Standards, policies, and practices 
  •       A new mindset for affinity application, evaluation, and authorization
  •       The advantages of recombinant antibody production methods over monoclonal and polyclonal antibody production methods.
  •       Phage display antibody production be adapted to produce the characteristic desired in applications such as multiple epitope recognition, tissues, and phenotype functional antibodies. 
  •       Learn about protein chemistry and conjugation of antibody and drug
  •       Immobilize antibody onto different polymers, nanoparticles, liposome  
Wednesday, February 21, 2018
Folding- and dynamics-based electrochemical biosensors

Folding- and dynamics-based electrochemical biosensors

Professor Rebecca Lai | University of Nebraska-Lincoln

Hosted by Professor Jill Venton

This seminar will cover the recent advances in the design and fabrication of folding- and dynamics-based electrochemical biosensors. These devices, which are often termed electrochemical DNA (E-DNA), aptamer-based (E-AB), and peptide-based (E-PB) sensors, are fabricated via direct immobilization of a thiolated and methylene blue (MB)-modified oligonucleotide or peptide probe onto a gold electrode. Binding of an analyte to the probe changes its structure and/or flexibility, which, in turn, influences the electron transfer between the MB label and the interrogating electrode. These sensors are resistant to false positive signals arising from the non-specific adsorption of contaminants and perform well even when employed directly in whole blood, saliva, and other realistically complex sample matrices. Furthermore, because all of the sensing components are chemisorbed onto the electrode surface, they are readily regenerable and reusable. Our results show that many of these sensors have achieved state-of-the-art sensitivity while offering the unprecedented selectivity, reusability and operational convenience of direct electrochemical detection.

 

Friday, February 23, 2018
Spring Break Begins

Spring Break Begins

Friday, March 2, 2018

Alumni Corner

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