Research Facilities

UVA Chemistry People

EPR Laboratory

The department has four EPR spectrometers with multifrequency and pulsed capabilities

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UVA Chemistry People

EPR Laboratory


Electron paramagnetic resonance (EPR) spectroscopy is an important tool for the determination of molecular structure and dynamics. Presently, the Department maintains three cw EPR spectrometers (with X- and Q-band), a Bruker ESM, a Varian E-line spectrometer, and a Bruker ELEXSYS 500. In addition, the department has an ELEXSYS580 Pulsed DEER Bruker spectrometer.

The EPR spectrometers are maintained by the Cafiso and Columbus Laboratories. If you have questions about:

  • Bruker EMX contact Wei-Wei Kuo
    Instructions for the Bruker EMX
  • Varian and Bruker Q-band contact Brett Kroncke
  • Instructions for the Varian

Chemistry

Hi-Resolution Mass Spectrometer

The Department of Chemistry has two Hi-Resolution Mass Spectrometers. 

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Chemistry

Hi-Resolution Mass Spectrometer


The Agilent LC-QTOF is located in Chem 175.  The instrument is used to separate components based on their affinity for the stationary phase of the LC column, while the quadrupole time-of-flight MS provides high resolution analysis of the separated compound based on highly accurate time-of-flight measurements.  This provides mass to charge ratios reportable to 4 decimal places.  QTOF is a valuable confirmation technique for synthesis and drug discovery because the chance that a different compound has the same exact mass is extremely low.

LC system: Agilent 1260 Infinity II Prime

Components:

*800 bar pump, 0.1 - 5.0 ml/min flow rate

*Heated column compartment

*66 vial autosampler, 0.1 - 40.0 ul injection volume

 

 

MS system: Agilent 6545B QTOF

Components:

*Agilent Jet Stream dual ESI source: analysis of positively or negatively charged ions by electrospray ionization (ESI); reference nebulizer continually introduces reference mass solution to provide drift correction; superheated nitrogen concentrates ions and increases sensitivity

6545B:

*Quadrupole time-of-flight instrument provides resolution of ~20,000 (100 m/z) - 45,000 (>1000 m/z) that is independent of acquisition rate

*MS mode allows all ions to be transmitted through quadrupole

*MS/MS mode allows only selected ions to pass through quadrupole.  Ions are then fragmented in collision cell for further characterization

*Instrument can operate in 1700 m/z, 3200 m/z, and 10000 m/z mass range

*Extended dynamic range mode uses high gain and low gain channel to provide up to 5 orders of linear dynamic range.  Results of each channel are stitched together to create the resulting spectrum.  Both trace and bulk components in a sample can be observed.  The resolution is cut in half using this mode.

*Acquisition rate of up to 50 spectra/sec for MS and 33 spectra/sec for MS/MS

*Mass accuracy as low as 0.8 ppm for MS and <2 ppm for MS/MS

*Femtogram scale sensitivity


Chemistry

Nanoscale Materials Characterization Facility

The Nanoscale Materials Characterization Facility (NMCF) is a state-of-the-art user facility located with the Materials Science and Engineering Dept (MSE).The facility is dedicated to materials characterization, available for use by all qualified faculty, students and researchers at UVa, as well as by researchers from other universities and industries.

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Chemistry

Nanoscale Materials Characterization Facility


The Nanoscale Materials Characterization Facility (NMCF) is a state-of-the-art user facility located with the Materials Science and Engineering Dept (MSE).The facility is dedicated to materials characterization, available for use by all qualified faculty, students and researchers at UVa, as well as by researchers from other universities and industries.


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UVA Chemistry People

NMR Facilities

Solution and solid-state NMR facility for biomolecule and chemical characterization

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UVA Chemistry People

NMR Facilities


NMR Spectroscopy Core Facility

The UVa NMR Spectroscopy Core Facility has five spectrometers for solution samples and one for solid samples. The solution spectrometers include two with cryogenically cooled probes (800 and 600 MHz) and three (two 600 and one 500 MHz) with room temperature probes. The 600 spectrometer with cryoprobe also has an automatic sample changer for unattended, multiple sample data collection. The solids spectrometer has a 500 MHz magnet and several probes that can obtain wideline and high resolution spectra; samples can be spun at rates up to 60 kHz. The spectrometers perform a wide range of experiments for characterization of molecular structure, interactions, and dynamics. The facility is supported by the UVa Medical School and the College of Arts and Sciences and is available to all. Further information is available here https://med.virginia.edu/biomolecular-magnetic-resonance-facility/.


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Small Molecule X-ray Diffraction

This facility is equipped to determine the crystal structures of small molecules

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Small Molecule X-ray Diffraction


(434) 924-7862

Many of you are becoming familiar with the instrumentation you will be using for your research…so here is some help – a short presentation of the X-ray instruments available at the Nanoscale Materials Characterization Facility (NMCF) of the Materials Science and Engineering (MSE) Department.

The NMCF facility serves all UVA science and engineering departments. The NMCF also houses several powerful SEM and TEM electron microscopes, as well as Auger spectroscopy and surface Raman systems. Training on all of these instruments is available.

If you are interested in using any of the X-ray instruments please contact me:

Dr. Diane Dickie, Head, X-ray Diffraction Section
NMCF, MSE Department

MS Building Room 103
Phone: TBA
E-mail: dad8v@virginia.edu

 

 


Chemistry

Stockroom

Carries most common chemical and supplies for the teaching and research laboratories

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Chemistry

Stockroom

Hours: 9:00am - 4:00pm

The stockroom is located in the Chemistry Building, at the loading dock on the second floor, and carries most common chemical and supplies for the teaching and research laboratories. Students, faculty, and staff are notified daily of deliveries and pick them up at the stockroom. Dan Via is the stockroom manager.

Stockroom Hours

Open 9 AM until 4 PM
Effective 02/22/12 we will be open M-F from 9 a.m.-4 p.m and will no longer be closed from 12-2.

During Holidays the hours are limited and will be posted here.

Stockroom Catalog

Today’s Incoming Shipments to the Stockroom

The following labs have incoming shipments ready for pick up 04/30/15:

Cafiso
Gahlmann
Gunnoe
Hsu
Landers
Lehmann

Order Tracker

Stockroom Forms

Forms (Word Document)

Request Items for Pickup


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University of Virginia Computation and Data Resource Exchange

Designed to simplify the process of finding local research technology solutions

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University of Virginia Computation and Data Resource Exchange


CADRE is a University-wide exchange designed to simplify the process of finding local research technology solutions. The CADRE website provides a comprehensive list of the software, services, training opportunities, storage solutions, and computational hardware available to UVA scholars. CADRE is multi-disciplinary and supports all eleven schools of the University.


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