Upcoming Seminars

All seminars are held at 3:30 PM in the Mechanical Engineering Building (MEC) Room 205 unless otherwise noted.

Spring 2020

Apr
03

VISITATION WEEKEND HAS BEEN CANCELLED

VISITATION WEEKEND HAS BEEN CANCELLED

Apr
10

SPRING SEMINARS HAVE BEEN CANCELLED

SPRING SEMINARS HAVE BEEN CANCELLED

ABSTRACT

Antisense Oligonucleotide Therapeutics for Neurological Diseases

Antisense oligonucleotides (ASOs) are synthetic, chemical modified nucleic acid analogs designed to bind to RNA by Watson-Crick base paring and upon binding, modulate the function of the targeted RNA. There are a variety of mechanisms by which ASOs can modulate RNA function dependent on the chemical design of the ASO, the type of RNA and where on the RNA the ASO is designed to bind. Both protein coding, as well as non-coding RNAs, can be targets of ASO based drugs, significantly broadening therapeutic targets for drug discovery compared to small molecules and protein-based therapeutics. The recent approval of nusinersen (Spinraza™) as a treatment for spinal muscular atrophy (SMA) and inotersen (Tegsedi) for polyneuropathy of hereditary transthyretin-mediated amyloidosis (hATTR)  validates the utility of antisense drugs for the treatment of neurological  diseases. A summary of the progress, lessons learned and future challenges applying antisense technology for neurological diseases will be provided.

Apr
15

SPRING SEMINARS HAVE BEEN CANCELLED

SPRING SEMINARS HAVE BEEN CANCELLED

Apr
17

SPRING SEMINARS HAVE BEEN CANCELLED

SPRING SEMINARS HAVE BEEN CANCELLED

Apr
17

SPRING SEMINARS HAVE BEEN CANCELLED

SPRING SEMINARS HAVE BEEN CANCELLED

Apr
24

SPRING SEMINARS HAVE BEEN CANCELLED

SPRING SEMINARS HAVE BEEN CANCELLED

Fall 2020

Aug
28

CHEMISTRY DEPARTMENT KICK-OFF SEMINAR

CHEMISTRY DEPARTMENT KICK-OFF SEMINAR

Dr. Rebecca Pompano | University of Virginia Department of Chemistry

Professor Jill Venton
Dr. Rebecca Pompano | University of Virginia Department of Chemistry
Hosted by Professor Jill Venton
Sep
04

Dr. Jefferson Chan|University of Illinois, Urbana Champagne

Dr. Jefferson Chan|University of Illinois, Urbana Champagne

Professor Clifford Stains
Hosted by Professor Clifford Stains
Sep
11

Dr. Jin Zhang | University of San Diego

Dr. Jin Zhang | University of San Diego

Professor Andreas Gahlmann
Hosted by Professor Andreas Gahlmann
Sep
18

Dr. Frieder Jaekle | Rutgers University, Newark

Dr. Frieder Jaekle | Rutgers University, Newark

Professor Robert Gilliard
Hosted by Professor Robert Gilliard
Sep
23

WEDNESDAY: DATE IS AVAILABLE

WEDNESDAY: DATE IS AVAILABLE

Sep
25

Dr. Dmitri Talapin | University of Chicago

Dr. Dmitri Talapin | University of Chicago

Dr. Sen Zhang
Hosted by Dr. Sen Zhang
Oct
02

Dr. Jerry Meyer | University of North Carolina

Dr. Jerry Meyer | University of North Carolina

Professor Charlie Machan
Hosted by Professor Charlie Machan
Oct
08

Possible Graham Lecture| To be determined

Possible Graham Lecture| To be determined

Oct
09

Hold Until Graham Lecture Scheduled

Hold Until Graham Lecture Scheduled

Oct
15

Possible Graham Lecture| To be determined

Possible Graham Lecture| To be determined

Oct
16

Hold Until Graham Lecture Scheduled

Hold Until Graham Lecture Scheduled

Oct
22

Possible Graham Lecture| To be determined

Possible Graham Lecture| To be determined

Oct
23

Hold Until Graham Lecture Scheduled

Hold Until Graham Lecture Scheduled

Oct
28

Dr. Chris Thomas | Ohio State University

Dr. Chris Thomas | Ohio State University

Professor Charlie Machan
Hosted by Professor Charlie Machan
Oct
29

Possible Graham Lecture To be determined

Possible Graham Lecture To be determined

Oct
30

Hold Until Graham Lecture Scheduled

Hold Until Graham Lecture Scheduled

Nov
06

Dr. William Pomerantz | University of Minnesota

Dr. William Pomerantz | University of Minnesota

Professor Marcos Pires
Hosted by Professor Marcos Pires
Nov
13

Dr. Bryan Dickinson | University of Chicago

Dr. Bryan Dickinson | University of Chicago

Professor Clifford Stains
Hosted by Professor Clifford Stains

Spring 2021

Jan
22

DATE AVAILABLE

DATE AVAILABLE

Jan
27

WEDNESDAY: DATE IS AVAILABLE

WEDNESDAY: DATE IS AVAILABLE

Jan
29

DATE AVAILABLE

DATE AVAILABLE

Feb
05

No Seminar: Candidacy Exams

No Seminar: Candidacy Exams

Feb
12

DATE AVAILABLE

DATE AVAILABLE

Feb
19

Dr. Jillian Dempsey | University of North Carolina

Dr. Jillian Dempsey | University of North Carolina

Professor Brent Gunnoe
Hosted by Professor Brent Gunnoe

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