Approaches to the Treatment of Alzheimer’s Disease: Two Targets; Two Modalities

ABSTRACT

Alzheimer’s disease remains a major unmet medical need representing a huge societal burden and a difficult event in the lives of patients and families. Current treatments do not offer hope for disease altering outcomes and recent attempts to bring forward new therapies have proven largely unsuccessful. This presentation will review two programs at Bristol-Myers Squibb spanning two therapeutic targets and two drug structural classes, or modalities: Small molecules and antisense oligonucleotides (ASOs). Efforts to improve the stereospecific synthesis of an important class of ASOs will be described.

Time and Location: 
3:30 PM | Mechanical Engineering Bldg (MEC) 205
Academic Year: 
2019
Event Date: 
Friday, November 15, 2019
Semester: 
Speaker: 
Professor Richard Olson
Speaker Title: 
Bristol-Myers Squibb
Host: 
Professor Ken Hsu